The APRT gene provides instructions for making an enzyme called adenine phosphoribosyltransferase (APRT). This enzyme is produced in all cells and is part of the purine salvage pathway, which recycles a group of DNA building blocks (nucleotides) called purines to make other molecules. The APRT enzyme helps to recycle the purine adenine to make a molecule called adenosine monophosphate (AMP). This conversion occurs when AMP is needed as a source of energy for cells.
Other Names
AMP diphosphorylase; AMP pyrophosphorylase; APRTase; APT_HUMAN
Related Genetics Topics
Identifiers
- NCBI Gene: 353
- OMIM: 102600
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
