The CASK gene provides instructions for making a protein called calcium/calmodulin-dependent serine protein kinase (CASK). The CASK protein is primarily found in nerve cells (neurons) in the brain, where it helps control the activity (expression) of other genes that are involved in brain development. It also helps regulate the movement of chemicals called neurotransmitters and of charged atoms (ions), which are necessary for signaling between neurons. Research suggests that the CASK protein may also interact with the protein produced from another gene, FRMD7, to promote development of the nerves that control eye movement (the oculomotor neural network).
Other Names
calcium/calmodulin-dependent serine protein kinase (MAGUK family); CAMGUK; CMG; CSKP_HUMAN; hCASK; LIN2; protein lin-2 homolog; TNRC8
Related Genetics Topics
Identifiers
- NCBI Gene: 8573
- OMIM: 300172
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
