The DNAJC5 gene provides instructions for making a protein called cysteine string protein alpha (CSPα). This protein is found near nerve cells in the brain, where it plays a role in the transmission of nerve impulses. Specifically, CSPα is part of a group (complex) of proteins that is found on the membrane of sac-like structures called synaptic vesicles. Synaptic vesicles are found close to the ends of nerve cells and contain chemical messengers that transmit signals from one nerve cell to another. CSPα is involved in recycling proteins that are involved in nerve impulse transmission by re-folding misshapen proteins so that they can be used in additional transmissions.
Other Names
CLN4; CLN4B; CSP; cysteine string protein alpha; DnaJ (Hsp40) homolog, subfamily C, member 5; dnaJ homolog subfamily C member 5; DNAJC5A; DNJC5_HUMAN; FLJ00118; FLJ13070
Related Genetics Topics
Identifiers
- NCBI Gene: 80331
- OMIM: 611203
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
