The FAS gene provides instructions for making a protein that is involved in cell signaling. Three FAS proteins group together to form a structure called a trimer, which then interacts with other molecules to perform its signaling function. This signaling initiates a process called a caspase cascade. The caspase cascade is a series of steps that results in the self-destruction of cells (apoptosis) when they are not needed.
Other Names
APO-1; apo-1 antigen; APO-1 cell surface antigen; apoptosis antigen 1; apoptosis-mediating surface antigen FAS; APT1; CD95; CD95 antigen; Fas (TNF receptor superfamily, member 6); Fas AMA; Fas antigen; FAS1; FASLG receptor; TNFRSF6; TNR6_HUMAN; tumor necrosis factor receptor superfamily member 6
Related Genetics Topics
- Autoimmune lymphoproliferative syndrome — MedlinePlus Genetics
- Juvenile idiopathic arthritis — MedlinePlus Genetics
Identifiers
- NCBI Gene: 355
- OMIM: 134637
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
