The GCM2 gene provides instructions for making a protein that is primarily found in the parathyroid glands. These four glands are located in the neck and produce a hormone called parathyroid hormone that regulates the levels of calcium in the blood. The GCM2 protein is needed for the development of the parathyroid glands before birth, and it plays a role in the maintenance of these glands into adulthood.
The GCM2 protein acts as a transcription factor, which means that it binds to specific regions of DNA and helps control the activity of genes. As a transcription factor, it is likely that the GCM2 protein helps produce parathyroid hormone.
Other Names
GCMB
Related Genetics Topics
Identifiers
- NCBI Gene: 9247
- OMIM: 603716
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
