The HJV gene provides instructions for making a protein called hemojuvelin. This protein is made in the liver, heart, and muscles used for movement (skeletal muscles). Hemojuvelin plays a role maintaining proper iron levels in the body by controlling the levels of another protein called hepcidin. Hepcidin is necessary for maintaining an appropriate balance of iron (iron homeostasis) in the body.
Other Names
hemochromatosis type 2 (juvenile); HFE2; HFE2A; JH; RGM domain family, member C; RGMC; RGMC_HUMAN
Related Genetics Topics
Identifiers
- NCBI Gene: 148738
- OMIM: 608374
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
