The KANSL1 gene provides instructions for making a member (subunit) of a group of interacting proteins called the KAT8 regulatory NSL complex. This complex is categorized as a histone acetyltransferase (HAT) complex. It helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes.
The protein produced from the KANSL1 gene is found in most organs and tissues of the body before birth and throughout life. By its involvement in controlling the activity of other genes, this protein plays an important role in the development and function of many parts of the body.
Other Names
CENP-36; centromere protein 36; DKFZP727C091; hMSL1v1; KANL1_HUMAN; KDVS; KIAA1267; male-specific lethal 1 homolog; MLL1/MLL complex subunit KANSL1; MSL1 homolog 1; MSL1v1; non-specific lethal 1 homolog; NSL complex protein NSL1; NSL1
Related Genetics Topics
Identifiers
- NCBI Gene: 284058
- OMIM: 612452
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
