The KAT6B gene provides instructions for making a type of enzyme called a histone acetyltransferase. These enzymes modify histones, which are structural proteins that attach (bind) to DNA and give chromosomes their shape. By adding a small molecule called an acetyl group to particular locations on histones, histone acetyltransferases control the activity of certain genes.
Little is known about the function of the histone acetyltransferase produced from the KAT6B gene. It is active in cells and tissues throughout the body, where it interacts with many other proteins. It appears to regulate genes that are important for early development, including development of the skeleton and nervous system.
Other Names
GTPTS; histone acetyltransferase KAT6B; histone acetyltransferase MORF; histone acetyltransferase MOZ2; histone acetyltransferase MYST4; K(lysine) acetyltransferase 6B; KAT6B_HUMAN; monocytic leukemia zinc finger protein-related factor; MORF; MOZ-related factor; MOZ2; MYST histone acetyltransferase (monocytic leukemia) 4; MYST-4; MYST4; qkf; querkopf; ZC2HC6B
Related Genetics Topics
- Coloboma — MedlinePlus Genetics
- Genitopatellar syndrome — MedlinePlus Genetics
- Ohdo syndrome, Say-Barber-Biesecker-Young-Simpson variant — MedlinePlus Genetics
Identifiers
- NCBI Gene: 23522
- OMIM: 150699
- OMIM: 601626
- OMIM: 605880
- OMIM: 614286
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
