The L2HGDH gene provides instructions for making an enzyme called L-2-hydroxyglutarate dehydrogenase. This enzyme is found in mitochondria, which are the energy-producing centers within cells. Within mitochondria, the enzyme participates in reactions that produce energy for cell activities. Specifically, L-2-hydroxyglutarate dehydrogenase converts a compound called L-2-hydroxyglutarate to another compound called 2-ketoglutarate. A series of additional enzymes further process 2-ketoglutarate to produce energy.
Other Names
2-hydroxyglutarate dehydrogenase; alpha-hydroxyglutarate oxidoreductase; alpha-ketoglutarate reductase; C14orf160; duranin; FLJ12618; L-alpha-hydroxyglutarate dehydrogenase; L2HDH_HUMAN
Related Genetics Topics
Identifiers
- NCBI Gene: 79944
- OMIM: 609584
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
