The MEOX1 gene provides instructions for making a protein called homeobox protein MOX-1, which is a member of the homeobox protein family. Homeobox proteins direct the formation of body structures during early development.
Homeobox protein MOX-1 is a transcription factor, which means it attaches to DNA and controls the activity (expression) of other genes. Through this function, the protein likely controls the expression of genes that regulate a process called somite segmentation. Somite segmentation separates the bones of the spine (vertebrae) from one another. Homeobox protein MOX-1 also ensures that the developing vertebral bone maintains the correct position for proper formation.
Additionally, the homeobox protein MOX-1 plays a role in the formation of the joints that connect the base of the skull and the top of spine (cranio-cervical joints).
Other Names
homeobox protein MOX-1; KFS2; mesenchyme homeo box 1; MOX1
Related Genetics Topics
Identifiers
- NCBI Gene: 4222
- OMIM: 600147
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
