The POLR3B gene provides instructions for making one part (subunit) of an enzyme called RNA polymerase III. This enzyme is involved in the production (synthesis) of ribonucleic acid (RNA), a chemical cousin of DNA. The RNA polymerase III enzyme attaches (binds) to DNA and synthesizes RNA in accordance with the instructions carried by the DNA, a process called transcription. RNA polymerase III helps synthesize several forms of RNA, including ribosomal RNA (rRNA) and transfer RNA (tRNA). Molecules of rRNA and tRNA assemble protein building blocks (amino acids) into working proteins; this process is essential for the normal functioning and survival of cells.
Other Names
C128; DNA-directed RNA polymerase III 127.6 kDa polypeptide; DNA-directed RNA polymerase III subunit B; DNA-directed RNA polymerase III subunit RPC2; DNA-directed RNA polymerase III subunit RPC2 isoform 1; DNA-directed RNA polymerase III subunit RPC2 isoform 2; FLJ10388; HLD8; polymerase (RNA) III (DNA directed) polypeptide B; polymerase (RNA) III subunit B; RNA polymerase III subunit C2; RPC2; RPC2_HUMAN
Related Genetics Topics
Identifiers
- NCBI Gene: 55703
- OMIM: 614366
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
