The RAI1 gene provides instructions for making a protein that is active in cells throughout the body, particularly nerve cells (neurons) in the brain. Located in the nucleus of the cell, the RAI1 protein helps control the activity (expression) of certain genes. Most of the genes regulated by RAI1 have not been identified. However, studies suggest that this protein controls the expression of several genes involved in daily (circadian) rhythms, such as the sleep-wake cycle. The RAI1 protein also appears to play a role in development of the brain and of bones in the head and face (craniofacial bones).
Other Names
KIAA1820; RAI1_HUMAN; SMCR; SMS
Related Genetics Topics
- Smith-Magenis syndrome — MedlinePlus Genetics
- Potocki-Lupski syndrome — MedlinePlus Genetics
- Yuan-Harel-Lupski syndrome — MedlinePlus Genetics
Identifiers
- NCBI Gene: 10743
- OMIM: 607642
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
