The RSPO2 gene provides instructions for making a protein called R-spondin-2. R-spondin-2 plays a role in the Wnt signaling pathway, a series of steps that affect the way cells and tissues develop. Wnt signaling is important for cell division, attachment of cells to one another (adhesion), cell movement (migration), and many other cellular activities.
During early development, Wnt signaling plays a critical role in growth and development of the skeleton and other tissues. The role of R-spondin-2 is to increase Wnt signaling. Specifically, R-spondin-2 attaches (binds) to certain proteins on the surface of cells to turn off (inactivate) proteins that block the Wnt pathway.
Other Names
cristin2; R-spondin family, member 2; R-spondin-2
Related Genetics Topics
Identifiers
- NCBI Gene: 340419
- OMIM: 610575
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
