The SBDS gene provides instructions for making a protein that is critical for building ribosomes. Ribosomes are cellular structures that process the cell’s genetic instructions to create proteins. Each ribosome is made up of two parts (subunits) called the large subunit and the small subunit. The SBDS protein helps prepare the large subunit so it can assemble into the ribosome by helping remove another protein (called eIF6) that blocks the interaction of the large subunit with the small subunit.
Research suggests that the SBDS protein may be involved in other cellular processes, such as ensuring proper cell division, aiding cell movement, protecting cells from stress, and processing RNA, a molecule that is a chemical cousin of DNA. More research is needed to clarify the protein’s role in these processes.
Other Names
CGI-97; FLJ10917; SBDS ribosome assembly guanine nucleotide exchange factor; SBDS, ribosome assembly guanine nucleotide exchange factor; SBDS_HUMAN; Sdol1; SDS; Shwachman-Bodian-Diamond syndrome; SWDS; YLR022c
Related Genetics Topics
Identifiers
- NCBI Gene: 51119
- OMIM: 607444
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
