The SLC17A5 gene provides instructions for producing a protein called sialin. This protein is located on the membranes of lysosomes, which are compartments in the cell that digest and recycle different types of molecules.
Sialin moves (transports) a molecule called free sialic acid to other parts of the cell. Sialic acid is produced when fats and proteins are broken down, and it plays an important role in cell communication and in the attachment of cells to one another (adhesion). Sialic acid is “free” when it is not attached (bound) to other molecules.
Other Names
AST; ISSD; NSD; SD; SIALIN; SLD; solute carrier family 17 (acidic sugar transporter), member 5; solute carrier family 17, (sodium phosphate cotransporter), member 5
Related Genetics Topics
Identifiers
- NCBI Gene: 26503
- OMIM: 604322
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
