The SLC25A4 gene provides the instructions for making a protein called adenine nucleotide translocase type 1 (ANT1). ANT1 functions in mitochondria, which are structures within cells that convert the energy from food into a form that cells can use. This process, called oxidative phosphorylation, converts adenosine diphosphate (ADP) into adenosine triphosphate (ATP), the cell’s main energy source. ANT1 forms a channel in the inner membrane of mitochondria. This channel allows ADP into mitochondria and ATP out of mitochondria to be used as energy for the cell. ANT1 may also be a part of another structure in the inner membrane called the mitochondrial permeability transition pore. This structure allows various molecules to pass into mitochondria and is thought to play a role in the self-destruction (apoptosis) of the cell.
Other Names
AAC1; adenine nucleotide translocator 1 (skeletal muscle); ADP,ATP carrier protein 1; ADP,ATP carrier protein, heart/skeletal muscle; ADP/ATP translocase 1; ADT1_HUMAN; ANT; ANT 1; ANT1; heart/skeletal muscle ATP/ADP translocator; PEO2; PEO3; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; T1
Related Genetics Topics
Identifiers
- NCBI Gene: 291
- OMIM: 103220
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
