The THAP1 gene provides instructions for making a protein that is a transcription factor, which means that it attaches (binds) to specific regions of DNA and regulates the activity of other genes. Through this function, it is thought to help control several processes in the body, including the growth and division (proliferation) of endothelial cells, which line the inside surface of blood vessels and other circulatory system structures called lymphatic vessels. The THAP1 protein also plays a role in the self-destruction of cells that are no longer needed (apoptosis).
Other Names
4833431A01Rik; DYT6; FLJ10477; nuclear proapoptotic factor; THAP domain containing, apoptosis associated protein 1; THAP domain protein 1; THAP domain-containing protein 1; THAP1_HUMAN
Related Genetics Topics
Identifiers
- NCBI Gene: 55145
- OMIM: 609520
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
