The WNT10A gene is part of a large family of WNT genes, which play critical roles in development starting before birth. These genes provide instructions for making proteins that participate in chemical signaling pathways in the body. Wnt signaling controls the activity of certain genes and regulates the interactions between cells during embryonic development.
The protein produced from the WNT10A gene plays a role in the development of many parts of the body. It appears to be essential for the formation of tissues that arise from an embryonic cell layer called the ectoderm. These tissues include the skin, hair, nails, teeth, and sweat glands. Researchers believe that the WNT10A protein is particularly important for the formation and shaping of both baby (primary) teeth and adult (permanent) teeth.
Other Names
OODD; protein Wnt-10a precursor; STHAG4; wingless-type MMTV integration site family, member 10A
Related Genetics Topics
Identifiers
- NCBI Gene: 80326
- OMIM: 150400
- OMIM: 224750
- OMIM: 257980
- OMIM: 606268
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
