The ABHD5 gene provides instructions for making a protein that turns on (activates) an enzyme called adipose triglyceride lipase (ATGL). The ATGL enzyme plays a role in breaking down fats called triglycerides, which are a major source of stored energy in cells. Cells primarily store triglycerides in structures called lipid droplets (also called adiposomes). The ABHD5 protein and the ATGL enzyme are found on the surface of lipid droplets. Once activated, the ATGL enzyme breaks down triglycerides in these structures to provide energy for the body.
Other Names
CGI58; comparative gene identification 58; IECN2; NCIE2
Related Genetics Topics
Identifiers
- NCBI Gene: 51099
- OMIM: 604780
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
