The ACADVL gene provides instructions for making an enzyme called very long-chain acyl-CoA dehydrogenase (VLCAD). This enzyme functions within mitochondria, the energy-producing centers in cells. Very long-chain acyl-CoA dehydrogenase is essential for fatty acid oxidation, which is the multistep process that breaks down (metabolizes) fats and converts them to energy.
Very long-chain acyl-CoA dehydrogenase is required to break down a group of fats called very long-chain fatty acids. These fatty acids are found in food and body fat. Fatty acids are a major source of energy for the heart and muscles. During periods without food (fasting), fatty acids are also an important energy source for the liver and other tissues.
Other Names
ACAD6; ACADV_HUMAN; acyl-CoA dehydrogenase, very long chain; acyl-coenzyme A dehydrogenase, very long chain; LCACD; VLCAD
Related Genetics Topics
Identifiers
- NCBI Gene: 37
- OMIM: 609575
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
