The ARSB gene provides instructions for producing an enzyme called arylsulfatase B, which is involved in the breakdown of large sugar molecules called glycosaminoglycans (GAGs). Specifically, arylsulfatase B removes a chemical group known as a sulfate from two GAGs called dermatan sulfate and chondroitin sulfate. Arylsulfatase B is located in lysosomes, compartments within cells that digest and recycle different types of molecules.
Other Names
ARSB_HUMAN; arylsulfatase B isoform 1 precursor; ASB; chondroitinase; chondroitinsulfatase; G4S; MPS6; N-acetylgalactosamine 4-sulfate sulfohydrolase; N-acetylgalactosamine-4-sulfatase
Related Genetics Topics
Identifiers
- NCBI Gene: 411
- OMIM: 611542
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
