The C2 gene provides instructions for making the complement component 2 protein. This protein helps regulate a part of the body’s immune response known as the complement system. The complement system is a group of proteins that work together to destroy foreign invaders (such as bacteria and viruses), trigger inflammation, and remove debris from cells and tissues. When a foreign invader is detected, the complement pathway is turned on (activated) and the complement component 2 protein attaches (binds) to a similar protein called complement component 4. Together, these proteins form a complex called C3 convertase, which triggers further activation of the pathway, allowing the proteins of the complement system to participate in an immune response.
Other Names
ARMD14; C3/C5 convertase; CO2; complement component 2; complement component C2
Related Genetics Topics
- Age-related macular degeneration — MedlinePlus Genetics
- Complement component 2 deficiency — MedlinePlus Genetics
Identifiers
- NCBI Gene: 717
- OMIM: 613927
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
