The CDC73 gene provides instructions for making a protein called parafibromin. This protein is found primarily in the nucleus of cells and is likely involved in regulating gene transcription, which is the first step in protein production. Parafibromin functions as a tumor suppressor, which means it keeps cells from growing and dividing (proliferating) too fast or in an uncontrolled way. When parafibromin is found outside the nucleus, it appears to be involved in the organization of the cell’s structural framework (the cytoskeleton).
Other Names
C1orf28; CDC73_HUMAN; cell division cycle protein 73 homolog; HRPT2; hyperparathyroidism 2 protein; hyrax; HYX; parafibromin
Related Genetics Topics
- Hyperparathyroidism-jaw tumor syndrome — MedlinePlus Genetics
- Familial isolated hyperparathyroidism — MedlinePlus Genetics
- Parathyroid cancer — MedlinePlus Genetics
Identifiers
- NCBI Gene: 79577
- OMIM: 607393
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
