The DGUOK gene provides instructions for making the enzyme deoxyguanosine kinase. This enzyme plays a critical role in mitochondria, which are the energy-producing centers inside the cell. Mitochondria each contain their own DNA, known as mitochondrial DNA or mtDNA, that is essential for their normal function. Deoxyguanosine kinase is involved in producing and maintaining the building blocks (nucleosides) that make up mtDNA.
Other Names
deoxyguanosine kinase, mitochondrial; DGK; dGK
Related Genetics Topics
- Deoxyguanosine kinase deficiency — MedlinePlus Genetics
- Progressive external ophthalmoplegia — MedlinePlus Genetics
Identifiers
- NCBI Gene: 1716
- OMIM: 601465
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
