The EMG1 gene provides instructions for making a protein that is involved in the production of cellular structures called ribosomes, which process the cell’s genetic instructions to create new proteins. Ribosomes are assembled in a cell compartment called the nucleolus.
The EMG1 protein is involved in the assembly of a part of the ribosome called the small subunit (SSU). In this role, the EMG1 protein functions as part of a protein complex called the SSU processome. In addition to helping to assemble the SSU, the SSU processome is involved in the maturation of a molecule called 18S rRNA, which is a chemical cousin of DNA that is incorporated into the SSU.
Other Names
18S rRNA (pseudouridine(1248)-N1)-methyltransferase; 18S rRNA (pseudouridine-N1-)-methyltransferase NEP1; 18S rRNA Psi1248 methyltransferase; C2F; EMG1 N1-specific pseudouridine methyltransferase; EMG1 nucleolar protein homolog; essential for mitotic growth 1; Grcc2f; NEP1; NEP1_HUMAN; ribosomal RNA small subunit methyltransferase NEP1; ribosome biogenesis protein NEP1
Related Genetics Topics
Identifiers
- NCBI Gene: 10436
- OMIM: 611531
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
