The FH gene provides instructions for making an enzyme called fumarase (also known as fumarate hydratase). Fumarase participates in an important series of reactions known as the citric acid cycle or Krebs cycle, which allows cells to use oxygen and generate energy. Specifically, fumarase helps convert a molecule called fumarate to a molecule called malate.
Other Names
fumarase; fumarase hydratase; FUMH_HUMAN; HLRCC; LRCC; MCL; MCUL1
Related Genetics Topics
- Fumarase deficiency — MedlinePlus Genetics
- Hereditary leiomyomatosis and renal cell cancer — MedlinePlus Genetics
- Primary macronodular adrenal hyperplasia — MedlinePlus Genetics
Identifiers
- NCBI Gene: 2271
- OMIM: 136850
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
