The FZD2 gene provides instructions for making a protein that plays a critical role in development before birth. The FZD2 protein interacts with other proteins (including those produced from the DVL genes, DVL1, DVL2, and DVL3) in chemical signaling pathways called Wnt signaling. These pathways control the activity of genes needed at specific times during development, and they regulate the interactions between cells when organs and tissues are forming. As a key part of Wnt signaling, the FZD2 protein is thought to be important for the normal development of the skeleton and potentially other parts of the body.
Other Names
frizzled 2, seven transmembrane spanning receptor; frizzled family receptor 2; frizzled homolog 2; frizzled-2 precursor; fz-2; Fz2; fzE2; hFz2
Related Genetics Topics
Identifiers
- NCBI Gene: 2535
- OMIM: 600667
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
