The GLA gene provides instructions for making an enzyme called alpha-galactosidase A. This enzyme is active in lysosomes, which are structures that act as recycling centers within cells. Lysosomes use digestive enzymes to process worn-out cell components and recycle usable parts.
Alpha-galactosidase A breaks down a molecule called globotriaosylceramide, which consists of three sugars attached to a fatty substance. This molecule is degraded as part of the normal recycling of old red blood cells (erythrocytes) and other types of cells.
Other Names
AGAL_HUMAN; Agalsidase alfa; Alpha-D-galactosidase A; alpha-D-galactoside galactohydrolase; Alpha-galactosidase; alpha-Galactosidase A; ceramidetrihexosidase; GALA; galactosidase, alpha; Melibiase
Related Genetics Topics
Identifiers
- NCBI Gene: 2717
- OMIM: 300644
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
