Anonychia congenita

Anonychia congenita is a condition that affects the fingernails and toenails. Individuals with this condition are typically missing all of their fingernails and toenails (anonychia). This absence of nails is noticeable from birth (congenital). In some cases, only part of the nail is missing (hyponychia) or not all fingers and toes are affected. All of the other tissues at the tips of the fingers and toes, including structures that usually support the nail and its growth (such as the nail bed), are normal.

Individuals with anonychia congenita do not have any other health problems related to the condition.

Other names

Absent nails; Anonychia; Aplastic nails; Congenital absence of nails; Hyponychia congenita

Inheritance pattern

Autosomal recessive

Related genes

RSPO4

Source: MedlinePlus Genetics, U.S. National Library of Medicine.