Spinocerebellar ataxia type 6

Spinocerebellar ataxia type 6 (SCA6) is a condition characterized by progressive problems with movement. People with this condition initially experience problems with coordination and balance (ataxia). Other early signs and symptoms of SCA6 include speech difficulties, involuntary eye movements (nystagmus), and double vision. Over time, individuals with SCA6 may develop loss of coordination in their arms, tremors, and uncontrolled muscle tensing (dystonia).

Signs and symptoms of SCA6 typically begin in a person's forties or fifties but can appear anytime from childhood to late adulthood. People with this disorder may require walking or mobility assistance later in life.

Other names

SCA6; Type 6 spinocerebellar ataxia

Inheritance pattern

Autosomal dominant

Related genes

CACNA1A

Source: MedlinePlus Genetics, U.S. National Library of Medicine.