The HEPACAM gene provides instructions for making a protein called GlialCAM. This protein is found in liver cells and certain brain cells known as glial cells. In liver cells, GlialCAM plays a role in the attachment of cells to one another (adhesion) and cell movement. In glial cells, GlialCAM attaches (binds) to other GlialCAM proteins or to other proteins called MLC1 and ClC-2. GlialCAM ensures that these proteins are transported to junctions that connect neighboring glial cells. The function of GlialCAM at the cell junction is unclear.
Other Names
FLJ25530; glial cell adhesion molecule; GlialCAM; HECAM_HUMAN; hepatocyte and glial cell adhesion molecule; hepatocyte cell adhesion molecule
Related Genetics Topics
Identifiers
- NCBI Gene: 220296
- OMIM: 611642
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
