The LSM11 gene provides instructions for making one piece (subunit) of a group of proteins called the U7 small nuclear ribonucleoprotein (snRNP) complex. In cells, the U7 snRNP complex plays an important role in processing molecules called messenger RNA (mRNA), which serve as the genetic blueprints for making proteins. The mRNA starts out as a molecule called pre-mRNA and must go through several processing steps before it is ready to make a protein. The U7 snRNP complex helps to process pre-mRNA. Specifically, the U7 snRNP complex targets the pre-mRNA of proteins called histones. Histones are structural proteins that attach (bind) to DNA and are necessary for copying a cell’s DNA before the cell divides (a process known as DNA replication).
Other Names
AGS8; FLJ38273; U7 SnRNA-Associated Sm-Like Protein LSm11
Related Genetics Topics
Identifiers
- NCBI Gene: 134353
- OMIM: 617910
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
