The MIR146A gene provides instructions for making microRNA-146a (miR-146a). MicroRNAs (miRNAs) are short lengths of RNA, a chemical cousin of DNA. These molecules control gene expression by blocking the process of protein production. MiR-146a is abundant in immature blood cells and controls the expression of hundreds of genes. This microRNA is thought to be involved in normal blood cell development. In particular, miR-146a appears to play a role in the growth and division of blood cells called megakaryocytes, which produce platelets, the cells involved in blood clotting.
Other Names
hsa-mir-146; hsa-mir-146a; miR-146a; MIRN146; MIRN146A; miRNA146A
Related Genetics Topics
Identifiers
- NCBI Gene: 406938
- OMIM: 610566
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
