The MYOC gene provides instructions for producing a protein called myocilin. Myocilin is found in certain structures of the eye, called the trabecular meshwork and the ciliary body, that regulate the pressure within the eye (intraocular pressure). Myocilin’s function is not well understood, but it may help to control the intraocular pressure through its action in the muscle tissue of the ciliary body.
Researchers believe that myocilin functions together with other proteins in the eye as part of the extracellular matrix, which is an intricate lattice that forms in the space between cells and provides structural support. Myocilin may interact with a number of other proteins that also function in the extracellular matrix.
Other Names
GLC1A; GPOA; JOAG; JOAG1; MYOC_HUMAN; myocilin, trabecular meshwork inducible glucocorticoid response; TIGR; trabecular meshwork-induced glucocorticoid response protein
Related Genetics Topics
Identifiers
- NCBI Gene: 4653
- OMIM: 137760
- OMIM: 601652
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
