The NF2 gene provides instructions for the production of a protein called merlin, also known as schwannomin. This protein is made in the nervous system, particularly in specialized cells called Schwann cells that wrap around and insulate nerves.
Merlin helps regulate several key signaling pathways that are important for controlling cell shape, cell growth, and the attachment of cells to one another (cell adhesion). This protein functions as a tumor suppressor, preventing cells from growing and dividing too fast or in an uncontrolled way.
Other Names
ACN; BANF; MERL_HUMAN; merlin; moesin-ezrin-radixin-like protein; SCH; schwannomerlin; schwannomin
Related Genetics Topics
Identifiers
- NCBI Gene: 4771
- OMIM: 156240
- OMIM: 607174
- OMIM: 607379
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
