The PDCD10 gene (also known as CCM3) provides instructions for making a protein that appears to play a role in the structure of blood vessels. While the exact function of the PDCD10 protein is unclear, studies suggest that it works with other proteins to help strengthen the interactions between cells and limit leakage from blood vessels. This protein is also thought to be involved in pathways that signal cells to self-destruct (undergo apoptosis) when they have completed a certain number of cell divisions or accumulated errors in their DNA.
Other Names
apoptosis-related protein 15; CCM3; cerebral cavernous malformation 3; PDC10_HUMAN; TFAR15
Related Genetics Topics
Identifiers
- NCBI Gene: 11235
- OMIM: 609118
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
