The PHF21A gene provides instructions for making a protein that helps regulate gene activity. The PHF21A protein does this by interacting with proteins that modify histones, which are structural proteins that bind to DNA and package it into chromosomes. Particular regions of the PHF21A protein can recognize certain histone patterns and help regulate whether certain genes are turned on (active) or turned off (inactive).
The PHF21A protein appears to be particularly important in regulating genes that are involved in the development of the brain and face.
Other Names
BHC80; BM-006; KIAA1696
Related Genetics Topics
Identifiers
- NCBI Gene: 51317
- OMIM: 608325
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
