The PRKAR1A gene provides instructions for making one part (subunit) of an enzyme called protein kinase A. This enzyme promotes cell growth and division (proliferation). Protein kinase A is made up of four protein subunits. Two of these subunits are called regulatory subunits because they control whether this enzyme is turned on or off. The PRKAR1A gene provides instructions for making one of these regulatory subunits. Protein kinase A remains off when the regulatory subunits are attached to the other two subunits of the enzyme.
Other Names
CAR; CNC1; PKR1; PRKAR1; Prkar1alpha; protein kinase A, RI-alpha subunit; protein kinase, cAMP-dependent, regulatory subunit type I alpha; protein kinase, cAMP-dependent, regulatory, type I, alpha; tissue-specific extinguisher 1; TSE1
Related Genetics Topics
Identifiers
- NCBI Gene: 5573
- OMIM: 188830
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
