The RBPJ gene provides instructions for making a protein called RBP-J, which is an integral part of a signaling pathway known as the Notch pathway. Notch signaling controls how certain types of cells develop in the growing embryo, including those that form the bones, heart, muscles, nerves, and blood. Signaling through the Notch pathway stimulates the RBP-J protein to attach (bind) to specific regions of DNA and control the activity of genes that play a role in cellular development.
Other Names
CBF-1; CBF1; H-2K binding factor-2; IGKJRB; IGKJRB1; RBP-J; RBP-J kappa; RBP-JK; RBPJK; RBPSUH; SUH; SUH_HUMAN
Related Genetics Topics
Identifiers
- NCBI Gene: 3516
- OMIM: 147183
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
