The RNASEH2C gene provides instructions for making one part (subunit) of a group of proteins called the RNase H2 complex. This complex is a ribonuclease, which means it is an enzyme that helps break down molecules that contain RNA, a chemical cousin of DNA. In particular, the RNase H2 complex helps break down a specific type of molecule that is made up of one strand of RNA and one strand of DNA (RNA-DNA hybrids). RNA-DNA hybrids are formed during DNA copying (replication) and are found in all cells.
The RNase H2 complex is also thought to be involved in DNA replication and error repair. This complex also likely plays an important role in the immune system by removing unnecessary pieces of DNA that might otherwise trigger an immune response.
Other Names
ribonuclease H2, subunit C; ribonuclease HI subunit C; RNase H1 small subunit; RNase H2 subunit C; RNH2C_HUMAN
Related Genetics Topics
Identifiers
- NCBI Gene: 84153
- OMIM: 610330
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
