The RPL5 gene provides instructions for making one of approximately 80 different ribosomal proteins, which are components of cellular structures called ribosomes. Ribosomes process the cell’s genetic instructions to create proteins.
Each ribosome is made up of two parts (subunits) called the large and small subunits. The protein produced from the RPL5 gene is among those found in the large subunit.
The specific functions of the RPL5 protein and the other ribosomal proteins within these subunits are unclear. Some ribosomal proteins are involved in the assembly or stability of ribosomes. Others help carry out the ribosome’s main function of building new proteins. Studies suggest that some ribosomal proteins may have other functions, such as participating in chemical signaling pathways within the cell, regulating cell division, and controlling the self-destruction of cells (apoptosis).
Research suggests that the protein produced from the RPL5 gene also normally has tumor suppressor function, which means that it helps keep cells from growing and dividing too rapidly or in an uncontrolled way.
Other Names
60S ribosomal protein L5; DBA6; L5; MGC117339; MSTP030; PPP1R135; RL5_HUMAN; uL18
Related Genetics Topics
Identifiers
- NCBI Gene: 6125
- OMIM: 603634
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
