The RPS6KA3 gene provides instructions for making a protein that is part of a family called ribosomal S6 kinases (RSKs). These proteins help regulate the activity of certain genes and are involved in signaling within cells. RSK proteins are thought to play a role in several important cellular processes including cell growth and division (proliferation), cell specialization (differentiation), and the self-destruction of cells (apoptosis).
The protein made by the RPS6KA3 gene appears to play an important role in the brain. The protein is involved in cell signaling pathways that are required for learning, the formation of long-term memories, and the survival of nerve cells.
Other Names
HU-2; HU-3; Insulin-stimulated protein kinase 1; ISPK-1; KS6A3_HUMAN; MAP kinase-activated protein kinase 1b; MAPKAPK1B; MRX19; p90(rsk); ribosomal protein S6 kinase, 90kDa, polypeptide 3; Ribosomal S6 kinase 2; RSK-2; RSK2
Related Genetics Topics
Identifiers
- NCBI Gene: 6197
- OMIM: 300075
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
