The SEPTIN9 gene provides instructions for making a protein called septin-9, which belongs to a group of proteins called septins. Septins are involved in a process called cytokinesis, which is the step in cell division when the fluid inside the cell (cytoplasm) divides to form two separate cells. The septin-9 protein also seems to act as a tumor suppressor, which means that it regulates cell growth and keeps cells from dividing too fast or in an uncontrolled way.
The SEPTIN9 gene seems to be found in cells throughout the body. Approximately 15 slightly different versions (isoforms) of the septin-9 protein may be produced from this gene. Different types of cells make different isoforms. However, the specific distribution of these isoforms in the body’s tissues is not well understood. Septin-9 isoforms interact with other septin proteins and help them perform their functions.
Other Names
SEPT9; SEPT9_HUMAN; SeptD1; septin D1; SINT1
Related Genetics Topics
Identifiers
- NCBI Gene: 10801
- OMIM: 604061
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
