The SOX9 gene provides instructions for making a protein that plays a critical role during embryonic development. The SOX9 protein is especially important for development of the skeleton and plays a key role in the determination of sex before birth. The SOX9 protein attaches (binds) to specific regions of DNA and regulates the activity of other genes, particularly those that control skeletal development and sex determination. On the basis of this action, the SOX9 protein is called a transcription factor.
Other Names
SOX9_HUMAN; SRA1; SRY (sex determining region Y)-box 9; SRY (sex-determining region Y)-box 9 protein; SRY box 9; transcription factor SOX9
Related Genetics Topics
- 46,XX testicular disorder of sex development — MedlinePlus Genetics
- Swyer syndrome — MedlinePlus Genetics
- Campomelic dysplasia — MedlinePlus Genetics
- Isolated Pierre Robin sequence — MedlinePlus Genetics
Identifiers
- NCBI Gene: 6662
- OMIM: 608160
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
