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Genes

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HRAS

The HRAS gene provides instructions for making a protein called H-Ras that is involved primarily in regulating cell division. Through a process known as signal transduction, the H-Ras protein relays signals from outside the cell to the cell's nucleus
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HSD17B10

The HSD17B10 gene provides instructions for making a protein called HSD10. This protein is located within mitochondria, the energy-producing centers inside cells, where it has several different functions. The HSD10 protein is important for the produc
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HSD17B3

The HSD17B3 gene provides instructions for making an enzyme called 17-beta hydroxysteroid dehydrogenase 3. This enzyme is active in the male gonads (testes), where it helps to produce the male sex hormone testosterone from a precursor hormone called
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HSD17B4

The HSD17B4 gene provides instructions for making the D-bifunctional protein. This protein is an enzyme, which means that it helps specific biochemical reactions take place. D-bifunctional protein is so named because it aids in two biochemical reacti
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HSD3B2

The HSD3B2 gene provides instructions for making the 3-beta-hydroxysteroid dehydrogenase (3β-HSD) enzyme. This enzyme is found in the gonads, which are the ovaries in females and testes in males, and in the adrenal glands, which are located on top of
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HSD3B7

The HSD3B7 gene provides instructions for making an enzyme called 3 beta-hydroxysteroid dehydrogenase type 7 (3β-HSD7). This enzyme is found in liver cells. It is embedded in the membrane of a cell structure called the endoplasmic reticulum, which is
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HSPB1

The HSPB1 gene provides instructions for making a protein called heat shock protein beta-1. This protein is a member of the heat shock protein family, which helps protect cells that are under stress from factors such as infection, inflammation, expos
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HSPB8

The HSPB8 gene provides instructions for making a protein called heat shock protein beta-8. This protein is a member of the heat shock protein family, which helps protect cells that are under stress from factors such as infection, inflammation, expos
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HSPG2

The HSPG2 gene provides instructions for making a protein called perlecan. This protein is found in the extracellular matrix, which is the intricate lattice of proteins and other molecules that forms in the spaces between cells. Specifically, it is f
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HTRA1

The HTRA1 gene provides instructions for making a protein that is found in many of the body's organs and tissues. This protein is a type of enzyme called a serine protease, which has an active center that cuts (cleaves) other proteins into smaller pi
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HTT

The HTT gene provides instructions for making a protein called huntingtin. Although the exact function of this protein is unknown, it appears to play an important role in nerve cells (neurons) in the brain and is essential for normal development befo
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HYCC1

The HYCC1 gene provides instructions for making a protein called hyccin, which is active (expressed) throughout the nervous system. Researchers believe that hyccin is involved in the formation of myelin, which is the covering that protects nerves and
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