The TSC2 gene provides instructions for producing a protein called tuberin. Within cells, tuberin interacts with a protein called hamartin, which is produced from the TSC1 gene. These two proteins help control cell growth and division (proliferation) and cell size. Proteins that normally prevent cells from growing and dividing too fast or in an uncontrolled way are known as tumor suppressors. Hamartin and tuberin carry out their tumor suppressor function by interacting with and regulating a wide variety of other proteins.
Other Names
PPP1R160; TSC2_HUMAN; tuberin; tuberous sclerosis 2
Related Genetics Topics
Identifiers
- NCBI Gene: 7249
- OMIM: 191092
Source: MedlinePlus Genetics, U.S. National Library of Medicine.
