The LMNA gene provides instructions for making several slightly different proteins called lamins. The two major proteins produced from this gene, lamin A and lamin C, are made in most of the body's cells. These proteins are made up of a nearly identi READ MORE

The LMNB1 gene provides instructions for making the lamin B1 protein. Lamin B1 is a structural protein called an intermediate filament protein. Intermediate filaments provide stability and strength to cells. Lamin B1 is a scaffolding (supporting) com READ MORE

The LMX1B gene provides instructions for producing a protein that attaches (binds) to specific regions of DNA and regulates the activity of other genes. On the basis of this role, the LMX1B protein is called a transcription factor. The LMX1B protein READ MORE

The LORICRIN gene is part of a cluster of genes on chromosome 1 called the epidermal differentiation complex. These genes are involved in the formation and maintenance of the outer layer of skin (the epidermis), particularly its tough outer surface ( READ MORE

The LPAR6 gene provides instructions for making a protein called lysophosphatidic acid receptor 6 (LPA 6 ). This protein functions as a receptor. Receptor proteins have particular sites into which certain other proteins, called ligands, fit like keys READ MORE

The LPIN2 gene provides instructions for producing a protein called lipin-2. Researchers believe that this protein plays an important role in the processing of fats (lipid metabolism). It is also thought to help regulate inflammation, a normal immune READ MORE

The LPL gene provides instructions for making an enzyme called lipoprotein lipase. This enzyme is found primarily on the surface of cells that line tiny blood vessels (capillaries) within muscles and in fatty (adipose) tissue. Lipoprotein lipase play READ MORE

The LRP2 gene provides instructions for making a protein called megalin, which functions as a receptor. Receptor proteins have specific sites into which certain other proteins, called ligands, fit like keys into locks. Together, ligands and their rec READ MORE

The LRP5 gene provides instructions for making a protein that is embedded in the outer membrane of many types of cells. This protein is known as a co-receptor because it works with another receptor protein, frizzled-4 (produced from the FZD4 gene), t READ MORE

The LRRK2 gene provides instructions for making a protein called dardarin. The LRRK2 gene is active in the brain and other tissues throughout the body. One segment of the dardarin protein is called a leucine-rich region because it contains a large am READ MORE

The LSM11 gene provides instructions for making one piece (subunit) of a group of proteins called the U7 small nuclear ribonucleoprotein (snRNP) complex. In cells, the U7 snRNP complex plays an important role in processing molecules called messenger READ MORE

The LTBP4 gene provides instructions for making a protein that has multiple functions in the extracellular matrix, which is the intricate lattice of proteins and other molecules that forms in the spaces between cells. The LTBP4 protein controls the a READ MORE